Molecular Devices
- IonWorks Barracuda Plus Automated Patch Clamp System
For ion channel drug discovery from target validation to compound profiling
The IonWorks Barracuda® Plus System enables scientists to perform complex pharmacological
analysis such as use-dependent blockade of ion channels, while exploiting the time and cost
savings of automation. Now, a single platform provides an affordable, high-throughput solution for
voltage- and ligand-gated ion channel research for drug discovery screening and safety assessment.
⊙ Highest available throughput of 1100 to 6000 data points per hour
⊙ Low-cost IonWorks PatchPlate™ consumable to keep running costs down
⊙ Population Patch Clamp™ (PPC) recording for robust and reproducible recordings
⊙ Long assay windows, up to 30 minutes with stable ionic currents
⊙ Supports kinetic studies of use-dependent compounds
Replace manual methods
Easy to use - eliminates the need for labor intensive conventional patch clamp
Precise voltage control and high temporal resolution produces results similar to manual patch clamp methods
Long assay windows, up to 30 minutes, support the study of use-dependant blockers
Get the speed and benefits of automation at an affordable price
Peer reviewed studies show that IonWorks Barracuda recordings give comparable results to GigaSeal for most channels
Highest throughput available
-True 384 parallel acquisition of an entire 384-well planar PatchPlateTMConsumable in as little as 20 minutes
-Record up to 6000 data points per hour
Unmatched flexiblity for assay support and development
-Optimized for both LGIC and VGIC
-Add up to 8 compound additions per well - generate cumulative response data ideal for safety profiling
Automation solutions for walk-away operation up to six hours
Designed for accuracy and ease of use
Individual runs are fully automated
Easy access to plates and consumables
Unique cell delivery system minimizes cell usage - < 5 mL/run
Ultrasonic tip washer with two solution inputs eliminates compound carryover
CellPettor delivery of cell suspension minimizes on board cell usage when operating with or without optional cell management