powerlab

Molecular Devices

    IonWorks Barracuda Plus Automated Patch Clamp System

    For ion channel drug discovery from target validation to compound profiling


    The IonWorks Barracuda® Plus System enables scientists to perform complex pharmacological

    analysis such as use-dependent blockade of ion channels, while exploiting the time and cost

     savings of automation. Now, a single platform provides an affordable, high-throughput solution for

    voltage- and ligand-gated ion channel research for drug discovery screening and safety assessment.


    Highest available throughput of 1100 to 6000 data points per hour

    Low-cost IonWorks PatchPlate™ consumable to keep running costs down

    Population Patch Clamp™ (PPC) recording for robust and reproducible recordings

    Long assay windows, up to 30 minutes with stable ionic currents

    Supports kinetic studies of use-dependent compounds

     

    Replace manual methods

    Easy to use - eliminates the need for labor intensive conventional patch clamp

    Precise voltage control and high temporal resolution produces results similar to manual patch clamp methods

    Long assay windows, up to 30 minutes, support the study of use-dependant blockers

     

     

    Get the speed and benefits of automation at an affordable price

    Peer reviewed studies show that IonWorks Barracuda recordings give comparable results to GigaSeal for most channels

    Highest throughput available

       -True 384 parallel acquisition of an entire 384-well planar PatchPlateTMConsumable in as little as 20 minutes

       -Record up to 6000 data points per hour

    Unmatched flexiblity for assay support and development

       -Optimized for both LGIC and VGIC

       -​Add up to 8 compound additions per well - generate cumulative response data ideal for safety profiling

    Automation solutions for walk-away operation up to six hours

     

    Designed for accuracy and ease of use

    Individual runs are fully automated

    Easy access to plates and consumables

    Unique cell delivery system minimizes cell usage - < 5 mL/run

    Ultrasonic tip washer with two solution inputs eliminates compound carryover

    CellPettor delivery of cell suspension minimizes on board cell usage when operating with or without optional cell management