powerlab

Molecular Devices

    QPix 400 Series Microbial Colony Pickers



    Automated microbial colony picking systems that pre-screen markers prior to picking


    The QPix™ 400 series of microbial colony pickers offers the unique option to simultaneously detect

    colonies and quantify fluorescent markers in a pre-screening step before picking. QPix systems are

    used worldwide in over 600 installations in research institutes, sequencing facilities, biotech and

    pharmaceutical companies. QPix robotics developed a reputation for reliability and accuracy,

    when used in sequencing centers during the Human Genome project. 

     

    More than just colony pickers, these systems enable scientists to:

    Automate workflows from sampling and spreading to picking

    Pick the right colonies every time

    Efficiently manage large, diverse populations for: protein expression,

        biofuel research, enzyme evolution, phage display, DNA sequencing, library generation and management


    Shorten Timelines, eliminate unnecessary work and expense downstream

    Use unique information to identify the best colonies

    Pre-screen colonies using white light and fluorescent imaging

    Accurately pick up to 30,000 selected colonies per day from trays or dishes



    Support more applications

    ⊙  Objective, quantitative pre-screening

    ⊙  Track fluorescent proteins

            - Compatible with broad range of fluorescent cloning vectors

            - Fuse fluorescent proteins with others to study protein folding or secretion, enzyme evolution or protein localization

            - Use as transformation markers or for mutation screens

     

    Fast Track Development of Constructs or Target Proteins

    ⊙  Automate and track entire workflow

    ⊙  From spreading* transformed cells to colony picking

    ⊙  Pre-screen to identify colonies with optimal expression levels

    ⊙  Accurately pick colonies of interest

    ⊙  Maintain subsequent clonal integrity


     

    Further Information

    ⊙  Validation of Next Generation Microbial Colony Pickers Using Fluorescence in a Complete Workflow Solution: Poster Download.

     

    Unmatched Performance

    ⊙  Pick the right colony every time

            - Use unique information to identify the best colonies

            - Pre-screen colonies using white light and fluorescent imaging

    ⊙  Picking efficiency >98%

            - Organism-specific pins maximize material transfer

            - Automatic calculation of agar height increases accuracy

    ⊙  Track entire sample history

            - Enhance visibility of history and location – tag important samples

            - Record and track sample histories from sample spreading* to picking, replication and re-arraying

     

     

     

    Systems tailored to workload and application requirements

    ⊙  QPix 460 System

         With a fully automated workflow, provides the greatest flexibility in application and experimental design

            - Automatically sample and spread from 1 x 96 well source plate into bioassay every 30 min.

            - Up to 140 destination plates in 2 stacker lanes

            - Sets up screening assays on filters or agar

            - Cherry-picks selected clones after off-line analysis

            - Spreading available only on QPix 460


    ⊙  QPix 450 System

          No automated spreading enables a greater number of destination plates

            - Up to 210 destination plates in 3 stacker lanes

            - Sets up screening assays on filters or agar

            - Cherry-picks selected clones after off-line analysis


    ⊙  QPix 420 System

          Full functionality in a bench-top format

            - Pick colonies into maximum 12 destination plates - ability to change plates for longer picking runs

            - Flexibility of plate positioning on the bed offers the ultimate performance in cherry picking selected clones