powerlab

Molecular Devices

    ImageXpress ULTRA™

     

     

    Benchtop Size의 Confocal Laser Scanning HCS System

    High Throughput Image Screening 에 대응한 자동화 Confocal Laser Scanning System 을 위해

    자동으로 이미지를 얻고, 자동으로 분석하는 완벽한 System 입니다.

     

    ImageXpress® Ultra System offers the ultimate solution when crisp, clear images are a priority. Controlled by state-of-the-art

    MetaXpress® Software, research-quality images of fixed- or live-cells are captured with high resolution. Diverse samples

    can be imaged with excellent signal-to-noise ratio, even when there is a high background, as in homogeneous, no-wash

    assays, or when samples are thick such as tissue sections or neurons growing in matrix.

     

     

     

    [Images of neurons were acquired and tiled from 6 sites. Each site is a long, continuous scan
    capturing a larger area with long neuronal features. Note that the neurites perfectly
    align across mutiple sites for easy quatification with our software algorithms]

     

     

              

                [Mouse kidney section stained for                                           [Neuronal processes can be measured and
              nuclei (blue), actin filaments (green) and                                  quantified with a Neurite Outgrowth Application
                    plasma membrane (red) ]                                                            Module in MetaXpress Software ]  
     
      

     

     

     

    True laser-scanning confocal system ensures a diverse set of samples can be imaged with excellent signal-to-noise ratio.

    ⊙ Software configurable detection pinhole provides two orders of magnitude of Z-resolution flexibility (from <1 µm to > 100 µm)

         over fixed-pinhole confocal systems.

    Simultaneous or sequential scanning with up to 4 solid state lasers facilitates simultaneous acquisition for optimal speed

         performance (up to 4 times faster than single laser). Unique sequential scanning is achieved in combination with high-resolution

         z-offset to correct for objective lens-induced chromatic aberrations.

    Fully-automated 100 nm resolution voice coil-driven stages provide positioning accuracy to capture intricate sub-cellular

         features as well as monitor long structures, such as neurons, across high-resolution tiled or stitched images.

    Software configurable field-of-view simplifies imaging of large objects like model organisms (C. elegans and zebrafish) and

         long structures similar to neuronal processes.

    Industry-leading autofocus option provides fast, reliable focusing with a dedicated 690 nm focus laser and ultra-fast sensors

        that will not bleach your sample while decreasing read times up to 5-fold.

    Custom design for screening enables capturing 25,000 wells per day in a 384-well microplate assay with a two color high quality

         assay (e.g.,Transfluor® beta-arrestin translocation assay). Lower resolution assays can be performed in excess of 100,000 wells/day.

    4-position automated objective changer eliminates manual objective changes and allows automated switching of magnifications

         during a single experiment.

    Universal plate holder facilitates image acquisition using any clear bottom plate from 6-well to 1536-well, in standard height,

         low profile, or low volume.

    Walk-away, 24/7 automation is achieved with the Thermo CRS CataLyst Express robotic plate handling system, enabling users to

         schedule multiple runs of one to three batches of 15 plates.